Neuroendocrine Tumor of Breast

Abstract

Rare and difficult breast cancer subtype neuroendocrine carcinoma of the breast (NECB). This study includes three NECB case cases to demonstrate its diagnostic and treatment challenges. Case Study 1 is a 34-year-old lady diagnosed with fibroadenoma who later developed neuroendocrine invasive ductal carcinoma. After mastectomy and Tamoxifen adjuvant chemotherapy, she had no recurrence at six months. Case Study 2 is a 48-year-old lady with NECB who responded to surgery and chemotherapy but developed liver and lung metastases. Chemotherapy and hormone treatment reduced metastases. Case Study 3 is a 50-year-old lady with poorly differentiated infiltrating breast cancer with neuroendocrine signs who had adjuvant chemotherapy, radiation, and hormone treatment without recurrence after six months.