A Study of Serum Iron and Ferritin Levels in Hypothyroid Patients- A Hospital Based Study

Abstract

 Introduction: Iron deficiency is one of the most common and preventable nutritional problem in India. Thyroperoxidase, an Iron containing enzyme is essential for initial 2 steps of thyroid hormone synthesis. So thyroid hormone may be altered in Iron deficiency. Ferritin is an iron storage protein found in almost all body tissues. Serum ferritin levels also have been reported to be altered in patients with thyroid disease. Metabolism of thyroid hormones and iron is quite inter- dependent. Deficiency of iron can produce hypothyroidism and vice versa. Materials & Method: This observational study was conducted in the department of Biochemistry at Tezpur Medical College and Hospital from January to July 2024.30 diagnosed hypothyroid patients were investigated for the levels of serum Iron and ferritin and compared with age and sex related healthy control group. Results: The results were analyzed using appropriate statistical test. The data compiled were analyzed with GraphPad Instat@ 3 Statistical Software. Conclusions: In our study we found that the levels of iron and ferritin were reduced in hypothyroid patients as compared to control groups. Hence, thyroid hormone insufficiency may lead to deficiency of serum iron and ferritin.