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Abstract
Background: Acute pancreatitis is a disease of great importance in clinical practice, defined as acute inflammatory process of the pancreas that may involve local tissues and affect other organs and requires intensive care. Methods: This prospective comparative observational study included patients with acute pancreatitis. Bedside index of severity in acute pancreatitis (BISAP) and PANC3 were used to stratify through severity of disease. Score from each model was compared to clinical severity defined by Revised Atlanta classification 2021for predicting complication and mortality. Sensitivity, specificity and accuracy were compared for each model. A p value of < 0.05 was significant. Results: It was seen that, 48 (82.8%) patients had mild to moderately severe acute pancreatitis, while 10 (17.2%) patients had severe acute pancreatitis. BISAP score had a higher sensitivity(88.24%) compared to PANC3 score (76.47%) whereas both had equal specificity for prediction of complications (95.12%). BISAP scoring model had a higher accuracy of 93% for predicting local complications as compared to PANC3 score (86%). Conclusions: BISAP score had more sensitivity, diagnostic accuracy, positive and negative predictive value, and equal specificity in predicting the severity of acute pancreatitis as compared to the PANC3 score. Hence, BISAP score was found to predict more number of patients with, the likelihood of progressing to severe disease.