Pleomorphic Invasive Lobular Carcinoma with Ductal Component: A Rare Mixed Tumour of Breast

Abstract

Introduction: Due to its uncommon nature, there exists a limited understanding of optimal treatment strategies and long-term prognosis for MDPLC. This report contributes to the existing knowledge base by presenting a unique case and potentially informing future treatment decisions. Aim: Among women globally, breast cancer stands as the most prevalent form of malignancy. Invasive ductal carcinoma (IDC) and invasive lobular carcinoma (ILC) dominate the diagnostic landscape. However, a rarer variant emerges where both these histological features intermingle within a single tumour, forming mixed ductal and pleomorphic lobular carcinoma (MDPLC). This case report delves into the experience of a patient diagnosed with MDPLC. This case report aims to present an unusual case of pleomorphic invasive lobular carcinoma with a ductal component, focusing on its distinctive histopathological features. It also seeks to explore the diagnostic challenges and treatment considerations involved in managing this rare mixed tumor in clinical practice